Latest Developments on:
- Circulating Tumor Cells (CTCs)
- Circulating tumor DNA (ctDNA)
- Circulating miRNAs (cfmiRNAs)
- Exosomes and extracellular vesicles (EVs)
Novel and established technologies in Liquid Biopsies:
- CTC isolation and detection systems
- Single-cell drug testing
- Epigenetic signatures
Clinical Applications on:
- Early detection
- Detection of minimal residual disease
- Cancer screening for patient selection
- Monitoring treatment response and drug resistance
- Liquid biopsy as a treatment-selection tool in advanced cancers
- Clinical trials
Implementation in Clinical Practice:
- Pre-analytical considerations, quality control
- Standardizing Liquid Biopsy for clinical use
- International Public-Private Partnerships on liquid biopsy
- Regulatory Considerations for Utilizing Liquid Biopsies in Drug and Diagnostics Development