Scientific Program

SCIENTIFIC PROGRAM
 
 

Day 1 | Wednesday, September 22nd, 2021

07:30 - 08:30 Registration
08:30 - 09:00 Welcome Address | Chairperson’s Opening Remarks
Opening Remarks: Evi Lianidou
(Greece)
Welcome address: M.A. Dimopoulos
(Greece)
09:00 -10:30 Plenary Lecture Session 1 | Liquid Biopsy as a tool to elucidate the biology of metastasis (Part 1)
Chairs: Jean-Paul Thiery (France) & Yibin Kang (USA)

09:00-09:30  PL1-1 | Klaus Pantel (Germany)| Liquid Biopsy: From Discovery to Clinical Application
09:30-10:00 PL1-2 | Catherine Alix-Panabières (France) | Metastasis-Initiator Circulating Tumor Cells: One of the keys to understand the biology of the metastatic cascade
10:00-10:30 PL1-3 | Andreas Trumpp (Germany) | CTC derived organoids from breast cancer patients
10:30 - 11:00 Poster Viewing and Networking Coffee Break
11:00 - 12:30 Plenary Lecture Session 1 | Liquid Biopsy as a tool to elucidate the biology of metastasis (Part 2)
Chairs: Jean-Paul Thiery (France) & Yibin Kang (USA)

11:00-11:30 PL1-4 | Danny R. Welch (USA) | Are mitochondrial DNA polymorphisms prognostic markers?
11:30-12:00 PL1-5 | Raghu Kalluri (USA) | The Biology and Clinical Translation of Exosomes
12:00-12:30 PL1-6 | Stuart S. Martin (USA) | Opportunities to target CTC cytoskeletal alterations to reduce metastasis
12:30 - 13:30 Lunch Break
13:30 - 14:30 Session 1 | Basic research in liquid biopsies (Oral Presentations) For details, click here
Chairs: Danny R. Welch (USA) & Stuart S. Martin (USA)

14:30 - 15:40 Industry Sponsored | Oral Presentations 1
Chair: Leon Terstappen (The Netherlands)

 14:30-15:00 Technologies for cell based liquid biopsy: future is getting closer
Gianni Medoro (Italy)
Sponsored by:
Platinum Sponsor
15:00-15:10 Comprehensive CTC analysis: Generating more information from liquid biopsies
Arturo Ramirez (USA)
Sponsored by:
Silver Sponsor
15:10-15:20 Development of standardized epithelial/mesenchymal CTC + PD-L1 assay for Parsortix system
Anne-Sophie Pailhes-Jimenez
(United Kingdom)
Sponsored by:
Silver Sponsor

 15:20-15:30 Capture and genomic analysis of single cancer cells using the malaria protein VAR2CSA
Mette Ørskov Agerbæk (Denmark)
 Sponsored by:
Silver Sponsor

 15:30-15:40 Harmonization of protocols for clinical use of liquid biopsy: See.d platform for pre-analytical, automated and standardized blood sample preparation for multi-analytes assays
Roberta Carbone, CSO, Tethis S.p.A.
 Sponsored by:
Silver Sponsor

15:40 - 16:30 Poster Session 1 & Networking Coffee Break
16:30 - 18:00 Plenary Lecture Session 2 | New insights on the potential of CTCs in liquid biopsy
Chairs: Klaus Pantel (Germany) & Andreas Trumpp (Germany)

16:30-17:00 PL2-1 | Yibin Kang (United States) | Targeting the stress-relieving pathways to prevent and reduce metastasis
17:00-17:30 PL2-2 | Jean-Paul Thiery (Singapore) | How to deal with the EMT phenotypes in carcinoma
17:30-18:00 PL2-3 | Nicola Aceto (Switzerland) | Biology and vulnerabilities of circulating tumor cell clusters
18:00 - 21:00 Welcome Reception

Day 2 | Thursday, September 23rd, 2021

09:00 - 10:30 Plenary Lecture Session 3 | Liquid biopsy in the clinic: breast cancer (Part 1)
Chairs: Massimo Cristofanilli (USA) & Jean-Yves Pierga (France)

09:00-09:30 PL3-1 | Clotilde Costa (Spain) | New approaches in liquid biopsy for breast cancer management
09:30-10:00 PL3-2 | Dave Hoon (USA) | Clinical Utility of Cell Free MicroRNA Signatures In Cancer Patients Plasma
10:00-10:30 PL3-3 | Wolfgang Janni (Germany) | PREDICT – An Up-Date on the global pooled analysis on the relevance of early CTC monitoring in patients with advanced breast cancer
10:30 - 11:00 Poster Viewing and Networking Coffee Break
11:00 - 12:00 Plenary Lecture Session 3 | Liquid biopsy in the clinic: breast cancer (Part 2)
Chairs: Wolfgang Janni (Germany) & Dave Hoon (USA)

11:00-11:30 PL3-4 | Massimo Cristofanilli (USA) | CTCs and ctDNA in breast cancer: translational research and real-world applications
11:30-12:00 PL3-5 | Jean-Yves Pierga (France) | Clinical applications of liquid biopsy in breast cancer management
12:00 - 13:00 Lunch Break
13:00 – 14:00 Session 2 | CTCs clinical applications (Oral Presentations)  For details, click here
Chairs: Clotilde Costa (Spain) & Stuart S. Martin (USA)
14:00 – 15:00 Industry Sponsored | Oral Presentations -2-
Chairs: Nickolas Stoecklein (Germany) & Evi Lianidou (Greece)

14:00-14:10 Integrating CTC Biology for the Development of Novel Therapeutics to Eradicate Cancer Metastases
Pritesh J Gandhi, PharmD, CEO, TellBio, Inc
Sponsored by:
Silver Sponsor

14:10-14:20 Urine as an emerging liquid biopsy
Stephanie Jordaens (Belgium)
Sponsored by:
Silver Sponsor


14:20-14:30 Crystal Digital PCR™ for the identification and quantification of low levels of cfDNA in liquid biopsy
Rémi Dangla, CTO, at Stilla Technologies
Sponsored by:
Silver Sponsor


 14:30-14:40 The Prediction of CTCs from Primary Tumors and Multiomic Characterization
Bruce Patterson, MD, CEO of IncellDX, San Carlos, California, United States
Sponsored by:
Silver Sponsor


14:40-14:50 Tools for detection and molecular characterization of circulating rare cells
Robert Zeillinger, Oncolab, Diagnostics Gmbh
Nicole Heinzl, Medical University of Vienna
Sponsored by:
Silver Sponsor

 14:50-15:00 COVID-19, Liquid Biopsy & the Future of Point-of-Care PCR testing.
Seth Egan (USA)
Cameron Gundry (USA)
Sponsored by:
Silver Sponsor

15:00 - 16:00 Poster Session 2 & Networking Coffee Break
16:00 - 16:30 Travel Award (Oral Presentations) For details, click here
Chairs: Evi Lianidou (Greece) & Catherine Alix-Panabières (France)
16:30 - 17:30 Plenary Lecture Session 4 | Liquid biopsy in the clinic: prostate cancer
Chairs: Dave Hoon (USA) & Michael Speicher (Austria)

16:30-17:00 PL4-1 | Emmanuel Antonarakis (USA) | Clonal hematopoiesis (CHIP) mutations in liquid biopsies from solid tumors: A diagnostic dilemma
17:00-17:30 PL4-2 | Howard Scher (USA) | Liquid biopsy: latest advances in prostate cancer

Day 3 | Friday, September 24th, 2021

09:00 - 10:30 Plenary Lecture Session 5 | Recent advances on the isolation, enumeration and molecular characterization of CTCs (Part 1)
Chairs: Evi Lianidou (Greece) & Leon Terstappen (The Netherlands)

09:00-09:30 PL5-1 | Richard J. Cote (USA) | Circulating Tumor Cells: New Approaches to Imaging and Analysis
09:30-10:00 PL5-2 | Nikolas Stoecklein (Germany) | Analysis of large blood volumes: enhancing CTC-based liquid biopsies for research and clinical applications
10:00-10:30 PL5-3 | Sabine Kasimir-Bauer (Germany) | Current challenges in ovarian cancer: Characterization of single circulating tumor cells and other liquid biopsy analytes for therapeutical approaches
10:30 - 11:00 Poster Viewing & Networking Coffee Break
11:00 - 12:00 Plenary Lecture Session 5 | Recent advances on the isolation, enumeration and molecular characterization of CTCs (Part 2)
Chairs: Nikolas Stoecklein (Germany) & Sabine Kasimir-Bauer (Germany)

11:00-11:30 PL5-4 | Leon Terstappen (The Netherlands) | What can we learn from Circulating Tumor Cells
11:30-12:00 PL5-5 | Evi Lianidou (Greece) | Development, validation, accreditation and clinical applications of molecular assays in liquid biopsy
12:00 - 13:00 Lunch Βreak
13:00 - 14:00 Session 3 | Novel Technologies in liquid biopsies (Oral Presentations) For details, click here
Chairs: Richard Cote (USA) & Sabine Kasimir-Bauer (Germany)
14:00 - 15:00 Plenary Lecture Session 6 | Novel technologies for ctDNA analysis
Chairs: Ellen Heitzer (Austria) & Evi Lianidou (Greece)

14:00-14:30 PL6-1 | Mike Makrigiorgos (USA) | New approaches for highly efficient and sensitive detection of cancer
biomarkers in liquid biopsies using digital droplet PCR, high resolution melting and NGS
14:30-15:00 PL6-2 | Viktor Adalsteinsson (USA) | Large cancer fingerprint screening for minimal residual disease
15:00 - 16:00 Poster Session 3 | Novel Technologies in liquid biopsies & Networking Coffee Break
16:00 - 17:30 Plenary Lecture Session 7 | Plenary Lecture Session 7 | Liquid biopsies: new potential in the clinical setting
Chairs: Catherine Alix-Panabières (France) & Nicholas Papadopoulos (USA)

16: 00-16:30 PL7-1 | Amanda Psyrri (Greece) | Liquid biopsy in head and neck cancer
16:30-17:00 PL7-2 | Michail Ignatiadis (Belgium) | Liquid biopsy enters the clinic: challenges ahead
17:00-17:30 PL7-3 | Caroline Dive (United Kingdom) | Personalised medicine for small cell lung cancer: is it getting closer?”
20:00 Gala Dinner Party
Travel Awards – Best Poster Awards

Day 4 | Saturday, September 25th, 2021

08:30 - 09:30 Session 4 | ctDNA clinical applications (Oral Presentations) For details, click here
Chairs: Ellen Heitzer (Austria) & Michael Speicher (Austria)
09:30 – 11:00 Plenary Lecture Session 8 | Circulating tumor DNA: technologies and applications in clinical practice
Chairs: Klaus Pantel & Michail Ignatiadis

09:30-10:00 PL8-1 | Ellen Heitzer (Austria) | The potential of ctDNA in clinical practice: From single gene to genome wide approaches
10:00-10:30 PL8-2 | Michael Speicher (Austria) | Deciphering open chromatin regions and epigenetic traces from plasma DNA
10:30-11:00  PL8-3 | Nicholas Papadopoulos (USA) | Liquid Biopsy and early detection of cancer
11:00 - 12:00 Panel Discussion  | Future directions in liquid biopsies

Moderator: Evi Lianidou (President Hellenic Society of Liquid Biopsy)
Panelists: Klaus Pantel (President, European Liquid Biopsy Society)
Massimo Cristofanilli (President, International Society of Liquid Biopsy)
Michail Ignatiadis (Chair Breast Cancer Group, EORTC)
12:00 Closing Remarks - End of the meeting
12:00 – 12:30 Light lunch
13.00 – 20.00 Visit to Ancient Olympia (archaeological site and museum) (optional)