Preliminary Scientific Program

DAY 1 • Sunday, 9 February 2020

10:00am - 6:00pm  REGISTRATION
8:00am - 12:30pm WORKSHOP
Hands-on MpMRI interpretation and MRI-TRUS fusion focal targeted therapy teaching course
Chairs: Rajan Gupta (USA), Ardeshir Rastinehad (USA), Arvin George (USA)
8:00am - 8:40am Segment 1: MRI Interpretation

MRI Course Director: Ardeshir Rastinehad (USA)
MRI Course Instructors: Peter Choyke (USA), Ismail Baris Turkbey (USA), Bradford Wood (USA), Peter Pinto (USA), John Feller (USA), Arnauld Villers (France), Rajan Gupta (USA)

> Introduction - Ardeshir Rastinehad (USA)
> MRI Structured Reporting - Ardeshir Rastinehad (USA)
> MRI Basics for a Urologist - Rajan Gupta (USA)
> MRI Pitfalls - Ismail Baris Turkbey (USA)
8:40am - 9:30am Workshop
(i). Lesion location via Structured Reporting

Chairs: Peter Choyke (USA), John Feller (USA)
(ii). Identify Lesions, Mark ROI of Lesion, Segment Prostate
Instructors: Peter Pinto (USA), Bradford Wood (USA), Rajan Gupta (USA), Ardeshir Rastinehad (USA), Arvin George (USA)
9:30am - 10:30am Segment 2: Fusion targeting / Case Setup - Workflows
Instructors: Leonard Marks (USA), Shyam Natarajan (USA), Arvin George (USA), Peter Pinto (USA), Ardeshir Rastinehad (USA), Osamu Ukimura (Japan)
10:30am - 10:45am Coffee Break
10:45am - 12:30pm Segment 3: Platforms and Performance of Focal Therapy - Talk with the Experts
> HIFU - Mark Emberton (United Kingdom)
> HIFU - Rafael Sanchez-Salas (France)
> Cryoblation - Thomas Polascik (USA)
> Irreversible Electroporation - Jean De La Rosette (Netherlands)
> Photodynamic Therapy - Andre Luis de Castro Abreu (USA)
> MRI guided laser ablation - John Feller (USA)
Q and A
12:30pm - 1:30pm Industry Sponsored Lunch
1:30pm - 3:30pm Workshop | Next Generation solution for today' prostate cancer Management
(Click here to view further information)
1:30pm - 3:30pm Prostate Consensus 1: Coming off active surveillance: Focal Therapy’s sweet spot?
Chairs: Thomas Polascik (USA)
1:30pm - 3:30pm Prostate Consensus 2: Biomarkers in prostate focal therapy
Chairs: Rafael Sanchez Salas (France)
1:30pm - 2:30pm Poster session 1: Diagnostic / Imaging
2:30pm - 3:30pm Poster session 2: Focal Therapies
3:30pm - 4:00pm Coffee break
4:00pm - 5:45pm Flagship Video Session: “This is how I do it”
1 Pt selection and PCa management
2 Robotic Approach to MRI-targeted + saturation biopsy - Kae Jack Tay (Singapore)
3 Focal Brachy
4 Focal Cryoablation of the prostate - Osamu Ukimura (Japan)
5 Perineologic transperineal prostate biopsy - Mike Gorin (USA)
6 Epigenetics and mapping - TBD - Dave Crawford (USA)
7 Boiling histotripsy for FT - Vera Khokhlova (USA) (UW)
8 CEUS for evaluation and follow up of FT - Andre Luis de Castro Abreu (USA)
9 Focal Ablation (This is how i do it)
5:45pm - 6:30pm Industry Sponsored Lecture
6:30pm - 8:00pm Welcome & Networking Reception

DAY 2 • Monday, 10 February 2020

8:00am - 8:45am Epidemiology and Active Surveillance
> Intelligent prostate cancer screening: Defining the need for precision diagnostics - Sigrid Carlsson (USA)
> Is AS after FT the same as de novo AS? - Laurie Klotz (Canada)
> Active Surveillance as an Alternative to Treatment for Small Renal Tumors - Phillip Pierorazio (USA) (JHH)
8:45am - 9:45am Patient Selection for Focal Therapy
  > Focal therapy for intermediate-high risk prostate cancer: expanding indications - Andre Luis de Castro Abreu (USA)
> Rationale for the high-risk primary patient - Mark Emberton (UK)
> Rationale for salvage focal therapy - Aaron Katz (USA)
> PT selection for renal ablation - Thomas Jarrett (USA)
> Prostate Consensus report 2020 - Thomas J. Polascik (USA)
9:45am - 10:15am Debate presentations: Can focal therapy replace prostatectomy in men with a localized, clinically significant lesion and a negative standard biopsy?
  Panelists: Mark Emberton (UK), Peter Carroll (USA)
10:15am - 10:45am
Coffee break
10:45am - 11:45am Biopsy Panel
  Moderator: David Crawford (USA)

> Patient Selection: How many bxs are minimally necessary vs too many? - Kae Jack Tay (Singapore)
> A Negative Fusion Biopsy. What did I miss and what is the next step? - Peter Pinto (USA)
> Renal Mass Biopsy: an underutilized technique. For whom and how? - Bradford Wood (USA)
> Targeted biopsy for planning FT - Leonard Marks (USA)
> Surveillance after FT: How to define success after focal therapy, MR targeted only vs MR Targeted and Standard Biopsy vs Imaging only - Herb Lepor (USA)
11:45am - 12:15pm Adjuncts and Immunotherapy as the holy grail
  Promise of Adjunct Immunotherapy
Combinatorial strategies to optimize Freezing insult - John Baust (USA)
12:15pm - 1:15pm Industry Lunch Symposium
(Click here to view further information)
1:15pm - 1:30pm How to start a focal therapy program for the General Urologist
  Moderators: Fernando Bianco (USA)
Speakers: Ardeshir Rastinehad (USA), Arvin George (USA)
1:30pm - 2:00pm Imaging Panel 1: Engineering and Imaging News Panel
  Moderators: Shyam Natarajan (USA), Kathy Nightingale (USA), Vera Khokhlova (USA)
> Molecular Imaging to Aid in the Histologic Characterization of Small Renal Tumors - Mike Gorin (USA)
> Computer Aided Detection of mpMRI - Anant Madabhushi (USA) [Case western]
> Artificial Intelligence based margin prediction - Shyam Natarajan (USA)
2:00pm - 2:40pm Imaging Panel 2: Multiparametric MRI
  Moderators: Rajan Gupta (USA), Peter Pinto (USA), Leonard Marks (USA)
> PIRADS 3 - worthy of targeted biopsy or low yield? - Peter Choyke (USA)
> mpMRI to detect recurrence - case presentations - Ismail Baris Turkbey (USA)
> mpMRI - Is the next step to improve the technology or the community expert reader - Rajan Gupta
2:40pm - 3:20pm mpUS and High Frequency Ultrasound
  Moderators: Christian Pavlovich (USA), Georg Salomon (Germany)
> Performance of micro-ultrasound imaging for diagnosis and treatment of PCa - David Crawford (USA)
> Multi-parametric ultrasound for targeting prostate cancer procedures - Kathy Nightingale (USA)
> Validating High frequency ultrasound with pathologic correlation - Jochen Walz (France)
> Using high frequency US and targeted biopsy platforms for FT - Daniel Rukstalis (USA)
3:20pm - 3:50pm Coffee break
3:50pm - 4:30pm Pathology, serum markers and genomic classifiers
  > Serum and urine biomarkers for prostate cancer [PHI, 4k, SelectMDx]: where do they integrate with MRI
> Tissue-based genomic classifiers for prostate cancer: can they help identify candidates for AS or FT [is there an impact on outcomes? - Peter Carroll (USA)
> NCI: How the genetics of renal cancers impacts clinical behavior and treatment decisions - Marston Linehan (USA) - NCI
> Interpreting prostate biopsies after focal therapy - Maria Merino (USA)
4:30pm - 5:30pm “From My Perspective”
  Moderator: Herb Lepor (USA)
> Why we need a Focal Therapy Society - Thomas Polascik (USA)
> How to engage industry to partner with academics to impact the field - Jean de la Rosette (Netherlands)
> Proposed New End-point for Localized, Low-risk Prostate Cancer Trials: Progression-free and Radical Treatment-Free Survival - Indy Gill (USA)
> Incorporating patient preference perspectives for novel PCa therapies - Charles Viviano (USA)

DAY 3 • Tuesday, 11 February 2020

7:15am - 7:30am Consensus 1 & 2
  Presentation of consensus II results
7:30am - 9:45am Trial updates: Latest prostate and kidney FT outcomes
> IRE Prostate - Jean De la Rosette (Netherlands)
> Gold Nanoparticles Multi-Institutional Trial- NCT02680535 - Art Rastinehad (USA)
> Boiling histotripsy for FT - Vera Khokhlova (USA) (UW)
> Fusion guided VLL Microwave
> Focal Radiotherapy - Soroush Rais-Bahrami (USA)
> Focal Brachytherapy - Danny Song (USA)
> Laser: Phase II outpatient MR-guided laser focal therapy: 10 yr interim results – John Feller (USA)
> Laser: FLA out of bore - Shyam Natarajan (USA)
> TACT study and MRI-guided Focal TULSA - Christian Pavlovich (USA)
> Partial anterior prostatectomy- Arnauld Villers (France)
> Prostate Cryoablation - 20 year experience TIPS and Tricks - Aaron Katz (USA)
> HIFU – European experience update - Rafael Sanchez Salas (France)
> Renal cryo - Pilar Laguna (Netherlands)
> Renal IRE and RFA – Jeffrey Cadeddu (USA)
> Radio-guided surgery - Georg Salomon (Germany)

9:45am - 10:15am Coffee break
10:15am - 10:45am Office-Based Procedures
  Moderator: Osamu Ukimura (Japan)
> Are we likely to acquire a code for fusion biopsy? - Norman Smith (USA)
> What can be done/coded in the office?
> Office Based MRI Fusion Targeted Prostate Cryoablation: 5 year outcomes with Tips and Tricks - Fernando Bianco (USA)
10:45am - 11:15am Focal Therapy Follow-up
  > Surveillance after focal therapy of the prostate (Japan Consensus) - Amir Lebastchi (USA)
> Defining radiologic success/failure after renal/prostate FT - Ismail Baris Turkbey (USA)
> How reliable is MRI for follow-up?
> How reliable is imaging vs biopsy after renal ablation and how to define success? - Bradford Wood (USA)
11:15am - 12:30pm Round table: “It didn’t work. Treatment of recurrence with Salvage therapy: which option?”
  Moderator: Danny Song (USA)
> When is additional FT reasonable vs surgery? - Jeffrey Cadeddu (USA)
> When is additional FT reasonable? - Osamu Ukimura (Japan)
> Salvage surgical treatment after FT prostate failure - Rafael Sanchez Salas (France)
12:30pm Closing Ceremony