Detailed Program

DAY 1 • Sunday, 9 February 2020
• Room: National A & B (Main Hall) •

07:00am - 6:00pm  REGISTRATION
7:30am - 12:30pm Hands-on MpMRI interpretation and MRI-TRUS fusion focal targeted therapy teaching course
Chairs: Rajan Gupta (USA), Ardeshir Rastinehad (USA), Arvin George (USA)
Room:National A & B (Main Hall)
7:30am - 8:10am


Segment 1: MRI Interpretation

MRI Course Director: Ardeshir Rastinehad (USA)
MRI Course Instructors: Peter Choyke (USA), Ismail Baris Turkbey (USA), Bradford Wood (USA), Peter Pinto (USA), John Feller (USA), Arnauld Villers (France), Rajan Gupta (USA)

> Introduction - Ardeshir Rastinehad (USA)
> MRI Structured Reporting - Ardeshir Rastinehad (USA)
> MRI Basics for a Urologist - Rajan Gupta (USA)
> MRI Pitfalls - Ismail Baris Turkbey (USA)
8:10am - 9:30am Workshop
(i). Lesion location via Structured Reporting

Chairs: Peter Choyke (USA), John Feller (USA), Peter Ka-Fung Chiu (Hong Kong)
(ii). Identify Lesions, Mark ROI of Lesion, Segment Prostate
Instructors: Peter Pinto (USA), Rajan Gupta (USA), Ardeshir Rastinehad (USA), Arvin George (USA), Jochen Walz (France), Fernando Bianco (USA), Mark Emberton (United Kingdom), Andre Luis de Castro Abreu (USA), Peter Ka-Fung Chiu (Hong Kong)
9:30am - 10:30am

Segment 2: Fusion targeting / Case Setup - Workflows
Instructors:  Arvin George (USA), Peter Pinto (USA), Ardeshir Rastinehad (USA), Osamu Ukimura (Japan), Andre Luis de Castro Abreu (USA), Christopher Dixon (USA), Fernando Bianco (USA), Mark Emberton (United Kingdom), Jochen Walz (France)

> Basics of MR US Fusion Guided Ablation – Fernando Bianco (USA)
> Basics of MR US Fusion Guided Ablation – Peter Pinto (USA)
> Basics of MR US Fusion Guided Ablation – Osamu Ukimura (Japan)
> Tips and Tricks Focal Ablation in 15 min rotations
10:30am - 10:45am Coffee Break
10:45am - 12:30pm

Segment 3: Platforms and Performance of Focal Therapy - Talk with the Experts

Moderators: Thomas J. Polascik (USA), Ardeshir Rastinehad (USA)

> HIFU - Mark Emberton (United Kingdom)
> HIFU - Rafael Sanchez-Salas (France)
> Cryoblation - Thomas Polascik (USA)
> Irreversible Electroporation - Jean De La Rosette (Netherlands)
> Photodynamic Therapy - Andre Luis de Castro Abreu (USA)
> MRI guided laser ablation - John Feller (USA)
Q and A
12:30pm - 1:30pm Lunch
1:30pm - 3:30pm Workshop | Next Generation solution for today's prostate cancer Management
(Click here to view further information)
Room: East Room
1:30pm - 3:30pm Prostate Consensus 1: Coming off active surveillance: Focal Therapy’s sweet spot?  Closed session - participation by invitation only
Chairs: Thomas Polascik (USA)          
Room: Ashlawn North
1:30pm - 3:30pm Prostate Consensus 2: Biomarkers in prostate focal therapy.  Closed session - participation by invitation only
Chairs: Rafael Sanchez Salas (France)  
Room: Ashlawn South
1:30pm - 3:30pm Poster session 1: Diagnostic / Imaging  |  PP01 - PP28
Moderator: Peter Choyke (USA), Vera Khokhlova (USA)
Room: Monticello East
1:30pm - 3:30pm Poster session 2: Focal Therapies  |  PP29 - PP59
Moderators: Shyam Natarajan (USA), Thomas J. Polascik (USA)
Room: Monticello West
3:30pm - 4:00pm Coffee break
4:00pm - 5:45pm Flagship Video Session: “This is how I do it”
Room: National A & B (Main Hall)
Chairs: Arvin George (USA), Daniel Rukstalis (USA)
1 "Trojan Horse" model for prostate cancer treatment using stromal vascular fraction (SVF) and oncolytic virus - John Feller (USA)
2 Robotic Approach to MRI-targeted + saturation biopsy - Kae Jack Tay (Singapore)
3 MRI Fusion Guided Prostate
Partial Gland Cryoablation Aided by a Virtual 3D Modeling: A step by step illustration - Ezequiel Becher (USA)
4 Focal Cryoablation of the prostate - Osamu Ukimura (Japan)
5 Perineologic transperineal prostate biopsy - Mike Gorin (USA)
6 Epigenetics and mapping - TBD - Dave Crawford (USA)
7 Boiling histotripsy for FT - Vera Khokhlova (USA) (UW)
8 CEUS for evaluation and follow up of FT - Andre Luis de Castro Abreu (USA)
9 Cryoablation of renal masses and outcome in pT1b tumors - Jochen Walz (France)
5:45pm - 7:00pm Welcome & Networking Reception

DAY 2 • Monday, 10 February 2020
• Room: National A & B (Main Hall) •

7:00am - 8:00am Industry Breakfast Symposium 
(Click here to view further information)
8:00am - 8:45am Epidemiology and Active Surveillance
   Moderators: Peter Carroll (USA), Arnauld Villers (France), Christopher Dixon (USA)
> Intelligent prostate cancer screening: Defining the need for precision diagnostics - Sigrid Carlsson (USA)
> Is AS after FT the same as de novo AS? - Laurie Klotz (Canada)
> Active Surveillance as an Alternative to Treatment for Small Renal Tumors - Phillip Pierorazio (USA)
8:45am - 9:45am Patient Selection for Focal Therapy
   Moderators:  Daniel Rukstalis (USA), Georg Salomon (Germany), Kae Jack Tay (Singapore)
  > Focal therapy for intermediate-high risk prostate cancer: expanding indications - Andre Luis de Castro Abreu (USA)
> Rationale for the high-risk primary patient - Mark Emberton (UK)
> Rationale for salvage focal therapy - Aaron Katz (USA)
> PT selection for renal ablation - Thomas Jarrett (USA)
> Tissue-based genomic classifiers for prostate cancer: Can they help identify candidates for AS or FT [Oncotype, Prolaris, Decipher] is there an impact on outcomes? - Peter Carroll (USA)
9:45am - 10:15am Debate presentations: Can focal therapy replace prostatectomy in men with a localized, clinically significant lesion and a negative standard biopsy?
  Moderators: Herb Lepor (USA), Andre Luis de Castro Abreu (USA), Laurie Klotz (Canada)
Mark Emberton (UK): PRO
Peter Carroll (USA): CON
10:15am - 10:45am
Coffee break
10:45am - 11:45am Biopsy Panel
  Moderator: Peter Ka-Fung Chiu (Hong Kong), David Crawford (USA), Soroush Rais-Bahrami (USA)

> Patient Selection: How many bxs are minimally necessary vs too many? - Kae Jack Tay (Singapore)
> A Negative Fusion Biopsy. What did I miss and what is the next step? - Peter Pinto (USA)
> Renal Mass Biopsy: an underutilized technique. For whom and how? - Timothy McClure (USA)
> Targeted biopsy for planning FT - Leonard Marks (USA)
> Surveillance after FT: How to define success after focal therapy, MR targeted only vs MR Targeted and Standard Biopsy vs Imaging only - Herb Lepor (USA)
11:45am - 12:15pm Adjuncts and Immunotherapy as the holy grail
  Chair: Phillip Pierorazio (USA), Rafael Sanchez Salas (France), Mark Emberton (United Kingdom)
  Promise of Adjunct Immunotherapy in Focal Therapy - Kwanghee Kim (USA)
Combinatorial strategies to optimize Freezing insult - John Baust (USA)
12:15pm - 1:15pm Industry Lunch Symposium
(Click here to view further information)
1:15pm - 1:30pm How to start a focal therapy program for the General Urologist
  Moderators: Fernando Bianco (USA), Leonard Marks (USA)
> Screening, Staging and Follow up - Ardeshir Rastinehad (USA)
> Focal Therapy Modality Selection, First Steps - Arvin George (USA
1:30pm - 2:00pm Imaging Panel 1: Engineering and Imaging News Panel
  Moderators: Shyam Natarajan (USA), Kathy Nightingale (USA), Vera Khokhlova (USA)
> Molecular Imaging to Aid in the Histologic Characterization of Small Renal Tumors - Mike Gorin (USA)
> Computer Aided Detection of mpMRI - Anant Madabhushi (USA) [Case western]
> Artificial Intelligence based margin prediction - Shyam Natarajan (USA)
2:00pm - 2:40pm Imaging Panel 2: Multiparametric MRI
  Moderators: Rajan Gupta (USA), Peter Pinto (USA), Leonard Marks (USA)
> PIRADS 3 - worthy of targeted biopsy or low yield? - Peter Choyke (USA)
> mpMRI to detect recurrence - case presentations - Ismail Baris Turkbey (USA)
> mpMRI - Is the next step to improve the technology or the community expert reader - Rajan Gupta (USA)
2:40pm - 3:30pm mpUS and High Frequency Ultrasound
  Moderators: Christian Pavlovich (USA), Georg Salomon (Germany), Laurence Klotz (Canada)
> Performance of micro-ultrasound imaging for diagnosis and treatment of PCa - David Crawford (USA)
> Multi-parametric ultrasound for targeting prostate cancer procedures - Kathy Nightingale (USA)
> Validating High frequency ultrasound with pathologic correlation - Jochen Walz (France)
> Using high frequency US and targeted biopsy platforms for FT - Daniel Rukstalis (USA)
> Proposed New End-point for Localized, Low-risk Prostate Cancer Trials: Progression-free and Radical Treatment-Free Survival – Inderbir Gill (USA)
3:30pm - 4:00pm Coffee break
4:00pm - 4:40pm Pathology, serum markers and genomic classifiers
  Moderators: David Crawford (USA), John Feller (USA)
Prostate Consensus report 2020 - Thomas J. Polascik (USA), Wei Phin Tan (USA)
> Serum and urine biomarkers for prostate cancer [PHI, 4k, SelectMDx]: where do they integrate with MRI - Timothy McClure (USA)
> How the genetics of renal cancers impacts clinical behavior and treatment decisions - William Marston Linehan (USA) 
> Interpreting prostate biopsies after focal therapy - Maria Merino (USA)
4:40pm - 5:30pm “From My Perspective”
  Moderator: Herb Lepor (USA), John Baust (USA), Daniel Rukstalis (USA)
> Why we need a Focal Therapy Society - Thomas Polascik (USA)
> How to engage industry to partner with academics to impact the field - Jean de la Rosette (Turkey)
> Incorporating patient preference perspectives for novel PCa therapies - Charles Viviano (USA)

DAY 3 • Tuesday, 11 February 2020
• Room: National A & B (Main Hall) •

7:15am - 7:30am Consensus 1 & 2 - Presentation of consensus II results
   Moderators: Thomas J. Polascik (USA), M. Pilar Laguna Pes (Turkey)
7:30am - 9:45am Trial updates: Latest prostate and kidney FT outcomes
Moderators:  Jochen Walz (France), Aaron Katz (USA), Kae Jack Tay (Singapore)
> IRE Prostate - Jean De la Rosette (Turkey)
> Gold Nanoparticles Multi-Institutional Trial- NCT02680535 - Ardeshir Rastinehad (USA)
> Boiling histotripsy for FT - Vera Khokhlova (USA)
> Fusion guided VLL Microwave - Roland Van Velthoven (Belgium)
> Focal Radiotherapy - Soroush Rais-Bahrami (USA)
> Focal Brachytherapy - Danny Song (USA)
> Laser: Phase II outpatient MR-guided laser focal therapy: 10 yr interim results – John Feller (USA)
> Laser: FLA out of bore - Shyam Natarajan (USA)
> TACT study and MRI-guided Focal TULSA - Christian Pavlovich (USA)

Moderators: Roland Van Velthoven (Belgium), Jean De La Rosette (Netherlands), Ardeshir Rastinehad (USA)
> Partial anterior prostatectomy- Arnauld Villers (France)
> Prostate Cryoablation - 20 year experience TIPS and Tricks - Aaron Katz (USA)
> HIFU – European experience update - Rafael Sanchez Salas (France)
> Renal cryo - M. Pilar Laguna Pes (Turkey)
> Renal IRE and RFA – Jeffrey Cadeddu (USA)
> Radio-guided surgery - Georg Salomon (Germany)
9:45am - 10:15am Coffee break
10:15am - 10:45am Office-Based Procedures
  Moderator: Osamu Ukimura (Japan), Christopher Dixon (USA), Peter Ka-Fung Chiu (Hong Kong)
> What can be done/coded in the office? 
> Are we likely to acquire a code for fusion biopsy? - Norman Smith (USA)
> Office Based MRI Fusion Targeted Prostate Cryoablation: 5 year outcomes with Tips and Tricks - Fernando Bianco (USA)
10:45am - 11:15am Focal Therapy Follow-up
  Moderators: Jeffrey Cadeddu (USA), John Feller (USA), Peter Ka-Fung Chiu (Hong Kong)
  > Surveillance after focal therapy of the prostate (Japan Consensus) - Amir Lebastchi (USA)
> Defining radiologic success/failure after renal/prostate FT - Ismail Baris Turkbey (USA)
> How reliable is MRI for follow-up? - Peter Pinto (USA)
> Special considerations for RCCA ablation in VHL & hereditary and definitely include some cool tech (fusion and CBCT tools) - Bradford Wood (USA)
11:15am - 12:30pm Round table: “It didn’t work. Treatment of recurrence with Salvage therapy: which option?” Case presentations
  Moderator: Danny Song (USA), Fernando Bianco (USA), Arnauld Villers (France)

Panelists: Jeffrey Cadeddu (USA), Osamu Ukimura (Japan), Rafael Sanchez Salas (France)
12:30pm Closing Ceremony

Closed session - participation by invitation only